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Looking specifically at studies which took into account a range of factors such as age, BMI, cholesterol and blood pressure, the team found that men smoking one cigarette a day have a 74% increased risk of coronary heart disease compared with never-smokers, while women who smoked one a day had a 119% increased risk

Some controversy still exists concerning the role of DA in reinforcing smoking behavior and no study has explored whether smoking increases DA concentrations at the D3 receptor, speculated to have a role in nicotines addictive potential

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